(1) Not only are acid and alkali albumens formed at the positive and negative poles respectively, but such chemical action extends humna aurainwards towards a neutral point in the interpolar space.

(2) The different action of the positive and negative poles respectively on cellular elements is most striking: the negative (kathode) dissolving the cell protoplasm and connective tissue, and setting free the nuclei, which stain readily with haematoxylin; the positive (anode), on the other hand, so modifying or destroying the nuclear elements, that they are no longer stainable by that reagent.

(3) The passage of the current leads to rise of arterial tension, not only in the vessels governed by the nerves situated in the interpolar area, but also in those governed by nerves in organic relation to the interpolar nerves through the medium of the spinal cord. For example, the action of a current passed through one arm led to changes in the circulation of the hand and wrist, not only of the side experimented on, but also of the other.

(4) The passage of the current has enormous influence on nutrition, as judged not only by its electrolytic action on albumens and fat, but by the changes effected under its influence in the constituents of the urine, which on an average was found to be affected thus: The specific gravity was but little altered, the acidity was diminished one-third, the urea was diminished one-tenth, the chlorides were increased nearly one-quarter, and the phosphates diminished nearly one-half.

(5) The positive pole is a most powerful haemostatic, and the negative a valuable derivative or counter-irritant.

(6) Under positive intra-uterine stimulus a fibroid hardens very much, and remains hard after the cessation of the current.
(7) The passage of the current is attended and followed by a feeling of well-being.

(8) During the passage of the current there is an alteration in sensibility to pain—an observation which was so far left incomplete, that I failed to point out that nerve sensibility in the neighbourhood of the positive pole is diminished (so that this pole is a valuable local anaesthetic), whilst there is a tendency to increased sensibility in the vicinity of the negative pole.

By John Shaw – The Cure of Cancer and how Surgery Blocks the Way